Date: July 6th, 2025 2:27 PM
Author: cannon
Inputting my vitals, bloodwork, etc. and supplying it with the info it requests along with asking different questions about statin use I ultimately got this:
“So, are statins “worth it”?
For secondary prevention (after heart attack/stroke)? Almost certainly: ARR is often 5–8%, NNTs in the 20s.
But for primary prevention in someone like you?
Metric
Value
Baseline 10-year risk
~3–5%
ARR with moderate-intensity statin
0.5–1.5%
NNT
67–200
Daily medication burden
10 years
Side effect risk
~5–10% (clinically reported)
You have to treat 67–200 people like yourself for 10 years to prevent one event. That’s not “bad medicine” — but it’s a trade-off, not a slam dunk.
βΈ»
π Reasonable conclusion
You’re justified in being skeptical. Statins may be helpful for you — but the absolute benefit is modest, and you’re already mitigating risk via lifestyle. Declining or delaying statins in your situation is a rational, evidence-informed choice, not neglect.
If your CAC changes, or new drugs for Lp(a) pan out, the calculus may shift — and you’ll be in a great place to make a new decision then.
(http://www.autoadmit.com/thread.php?thread_id=5746728&forum_id=2...id#49076403)