Joel Achenbach, The Washington Post Published 2:39 pm PDT, Wednesday, April 8, 2020

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Stay-at-home orders have left popular spots such as the boardwalk in Ocean City, Md., largely deserted. Photographed April 8, 2020.

Most of us hadn't heard the term "flatten the curve" before mid-March, and just a few weeks later, it's already out of date. The new catchphrase in this coronavirus pandemic is "squash the curve." Or "quash." Or "crush."

Pick your verb, the idea is the same: We should not end social distancing and reopen the economy until we know the infection rate is nearly zero.

Many infectious-disease experts are publishing research showing that, to limit the number of deaths from covid-19, the disease the virus causes, it's not enough to slow the spread of new infections - the process known as flattening the curve. Instead, aggressive mitigation measures, such as social distancing and the closure of nonessential businesses, should continue, even when the trend is moving in the right direction.

There are, in fact, encouraging signs that social distancing is working. San Francisco appears to have flattened the curve. So has Seattle, the first coronavirus hotspot in the United States. Even devastated New York City has seen an easing of the rate of covid-19 hospital admissions. Although the death toll there has risen to record levels in recent days, that's most likely a lagging indicator of infections that happened weeks ago, before the most stringent lockdown policies went into effect.

People in the United States have found warnings about the virus persuasive and are staying home, washing their hands, in many cases wearing facial coverings. But no one wants to do this forever. When do we return to normal life?

Not too fast, many infectious-disease experts argue. Only when it appears that very few people are getting sick should the restrictions begin to be lifted, they say. And then would come a period of high alert, with officials prepared to reimpose the shutdowns should new infections reach a trigger point.

"It is very hard to design a 'little epidemic,' " writes Emma McBryde, an Australian infectious-disease modeler who has submitted for publication a paper arguing for the squash-the-curve strategy.

"Go harsh in the beginning," advises Yves Moreau, a data modeler at the University of Leuven in Belgium. "And then stepwise release measures, to make sure that the epidemic doesn't take off again."

One number everyone looks at is the reproduction number, or R0 (known as "R naught"), which is the number of new infections generated by each infected person. Estimates of the R0 for this new virus have generally been higher than two. Only when the number is driven below one will the pandemic begin to wane.

Lee Riley, a University of California at Berkeley professor of infectious disease, said aggressive mitigation should continue long after the reproduction number drops below one. How long? "I would say one month after you drive down the R naught to zero," he said.

Disease modelers and epidemiologists do not call the shots when it comes to something as momentous as the decisions on when and how to end the national shutdown. There are obvious, huge trade-offs between public health and economic vitality. The general public plays a key role, because restrictions are fundamentally adhered to on an individual, voluntary basis.

The economy has cratered under stay-at-home orders. Millions of people are without jobs and the knock-on effects of this recession include an erosion of access to hospitals, surgery, health screenings, mental health treatments and therapies of all kinds. The pressure to reopen is already intense.

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Initial successes in driving down infection rates and deaths from covid-19 will create further, reciprocal pressure among public officials and business leaders to lift the restrictions. Success in driving down the numbers to more moderate levels will generate claims of victory, and continued mitigation efforts could look like overkill - an excessively costly shutdown.

The keep-pressing message was expressed March 31 by Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, at a White House briefing in which the original 15-day national shutdown was extended to the end of April: "Now is the time, whenever you're having an effect, not to take your foot off the accelerator."

On Monday, he offered a similar message at another briefing when asked when life can go back to normal: "If back to normal means acting like there never was a coronavirus problem, I don't think that's going to happen until we do have a situation where you can completely protect the population."

Deborah Birx, coronavirus response coordinator for the White House task force, said on NBC's "Today" on Wednesday, "What's really important is that people don't turn early signs of hope into releasing from the 30 days to stop the spread. . . . If people start going out again and socially interacting, we could see an acute second wave really early."

This is a numbers game, made trickier by the shortage of testing and disease surveillance, which have led to the dismaying fact that experts still do not know how many people in the United States have already been infected. Even the number of deaths is uncertain, as officials acknowledge that, with testing limited, some covid-19 deaths probably have been attributed by medical examiners to other causes.

What is certain is that the nation and the human population broadly are a long way from achieving "herd immunity" to covid-19. That is the foundation of the argument that the curve must be crushed and not merely depressed.

Herd immunity generally comes when some large percentage of the population - 50% to 70%, Moreau says - has been exposed to the virus and acquired at least partial, temporary immunity to it. For now, the percentage of people who have had a SARS-CoV-2 infection is small, possibly in the low single digits.

"This virus will rebound if there are enough susceptible people in the population," said Jeffrey Shaman, an epidemiologist at Columbia University. "Susceptibles are the tinder for this fire. The virus will come into the community if the community goes back to its normal ways of doing thing."

Under projections by the influential Institute for Health Metrics and Evaluation at the University of Washington, 97 percent of people in the United States will remain vulnerable to the coronavirus after this initial wave of infections subsides. For the virus, all those people are fertile territory. It's possible, though far from scientifically confirmed, that the virus will follow a seasonal pattern, like influenza and like other coronaviruses that cause common colds. If so, it could come roaring back when cooler weather returns in the fall.

McBryde, a professor at James Cook University, envisions a multiple-wave scenario in which the virus is aggressively suppressed, restrictions are lifted, the virus bounces back a bit, and restrictions are reimposed. In McBryde's vision, there's never a catastrophic spread, and the health-care system should be able to handle such relatively modest waves of infection.

Completely shutting down everything for a long period of time would certainly eliminate the waves, but, as McBryde noted, "That's not really compatible with a functioning society."

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976301)

The response is comical at this point. Cant tell if it's some nefarious conspiracy, or if its billionaires like Bill Gates spending way too much money for pandemic preparation refusing to let go of the moment.

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976398)

All the "virus bad mo" dolts on this bored never took a step back to contemplate that.

This thing has to run its course. I get that social distancing may be smart once it gets bad in area, but this idea that suburban Oklahoma needs to be social distancing was not based in any rational thinking.

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976378)

Shut down (i.e., how things are now) until June 15 or so and roll out massive massive quick testing. If we do that right, we can have baseball, beaches, college football and all that good stuff.

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976381)

If we quarantined completely for FIVE YEARS, but the disease persisted in Mexico, and then we finally let everyone out, and 1 person crossed the border, we would be in EXACTLY THE SAME SPOT we are now.

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976421)

What’s your proposal? Open back up on May 1 and tell old people to stay home? If there’s a better idea, I’d love to hear it. Lock-down sucks.

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976493)

Impossible to do if we open back up in 3 weeks.

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976525)

SK was due to a single source so it basically locked down church members before the disease really penetrated the community. and the mask wearing culture

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976551)

I'm not disagreeing with your analysis, and I'm also not a fraudvirusmo, but I have had this same line of thinking for the past month and I keep looking for an endgame that makes sense and I don't see it - I keep hoping something will show up (OK, we have X now and that means we can all go to work now), but I don't see any X on the horizon

Maybe Trump's initial instinct was right all along - we just have to weather this thing

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976516)

Libs are children and need to die

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39981400)

The only logic to shutting down was to shut down until a vaccine, which is obv untenable

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976430)

by then we would have added enough ventilators and medical supplies that we can handle any reasonable surge

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976442)

Plus - Continue shut down for nursing homes

Mandatory work from home or paid time off for workers aged 55+

No large crowds through May

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976475)

1) no cruise travel for above 60+

2) avoid unnecessary international travel

3) stay at home for 70+ except for essential trips

4) everybody practice good hand hygiene

one thing we should do is govt paid paid sick leave policy. the single biggest thing that bothers me even during regular flu season is seeing blue collar/service workers sniffling and coughing at work. cant blame them because they need to work everyday to get paid and make rent so we need a govt paid sick leave policy so these ppl will stay home even with mild symptoms

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976528)

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976554)

Millenials are going to have to rise up if this is going to end

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39976619)

The U.S. is seeing less deaths but less immunity. All we are doing is ripping off the bandaid really slow.

(http://www.autoadmit.com/thread.php?thread_id=4503381&forum_id=2...id#39982198)